#BETA BLOCKER ANTIDOTE SERIES#
#BETA BLOCKER ANTIDOTE FREE#

Non-selective (β 1 and β 2): carvedilol, labetolol (α blockade also), oxprenolol, pindolol, propranolol, nadolol, sotalol (class II and III antidysrhythmic properties), and timolol.Cardio-selective (β 1): atenolol, acebutolol, betaxolol, bisoprolol, esmolol, metoprolol, practolol.

#BETA BLOCKER ANTIDOTE FREE#

β 2 adrenergic receptors: beta-blockers limit smooth muscle relaxation and vasodilation (vascular beds), glycogenolysis and gluconeogenesis (liver), bronchodilation (lung), and the release of free fatty acids (adipose tissue).

β 1 adrenergic receptors: beta-blockers block the catecholamine effects of positive inotropy, dromotropy, and chronotropy.

Pathophysiology: Beta-blockers competitively inhibit catecholamines at beta-adrenergic receptors: 1.

Of these calls, 3,000 involved children under the age of 5.

poison centers received > 40,000 calls regarding beta-blocker exposures. What’s the next step in your evaluation and treatment? Neuro: Alert, interacting with caregiver, behavior appropriate for age.Ībdomen: soft, non-tender, non-distended. Triage vital signs (VS): BP 88/62, HR 77, T 99.1 Oral, RR 12, SpO2 99% on room air. Based upon the date of the prescription, the grandfather reports 10 tabs as unaccounted for. Per the patient’s mother, the toddler was left unattended for “seconds” at her grandparent’s home and was subsequently found holding her grandfather’s medication bottle, chewing the atenolol tabs. We’ll keep it short, while you keep that EM brain sharp.Ī 3-year-old female arrives in the emergency department approximately 15 minutes following the ingestion of an unknown amount of atenolol.

#BETA BLOCKER ANTIDOTE SERIES#

Welcome to an emdocs series designed to foster your working knowledge by providing an expedited review of clinical basics. Author: Erica Simon, DO, MHA EMS Fellow, SAUSHEC, USAF) and Daniel Sessions, MD (EM Associate Program Director, SAUSHEC, USA / Associate Medical Director, South Texas Poison Center) // Edited by: Alex Koyfman, MD EM Attending Physician, UTSW / Parkland Memorial Hospital) and Brit Long, MD EM Attending Physician, SAUSHEC, USAF)

Beta blocker antidote